A mosaic variant in MAP 2K1 is associated with giant naevus spilus‐type congenital melanocytic naevus and melanoma development

Malignant melanoma arising from a small congenital melanocytic naevus.

A 29-year-old woman presented with a subcutaneous nodule within a pigmented macule on her left neck. The elliptic macule measured 1266 mm (Fig. 1), and had been present since birth, judging from her family’s statements. The subcutaneous nodule had gradually grown within the macule 12 months previously. The flesh colour around the black macule had changed into a blue tone occurring with the nodu...

Congenital melanocytic naevus with atypical pigment network on dermoscopy.

Dysplastic melanocytic naevus syndrome.

Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma

Congenital malignant melanoma (CMM) is a rare condition that is defined as malignant melanoma recognized at birth. CMM may develop in utero in one of three ways: (1) transmission by metastasis through the placenta from a mother with melanoma; (2) primary melanoma arising within a giant congenital melanocytic naevus (GCMN); (3) primary de novo cutaneous CMM arising in utero. CMM can be confused ...

Proliferative nodule in small congenital melanocytic naevus after childhood.

© 2012 The Authors. doi: 10.2340/00015555-1186 Journal Compilation © 2012 Acta Dermato-Venereologica. ISSN 0001-5555 Congenital melanocytic naevi (CMNs) are divided into giant, medium-sized, and small types. Giant CMN measures more than 20 cm in maximal diameter, whereas small CMN measures less than 1.5 cm (1). The lifetime incidence of melanoma in giant CMN is estimated to be between 6.3% (2) ...